Low-frequency stimulation of the external globus palladium produces anti-epileptogenic and anti-ictogenic actions in rats
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چکیده
منابع مشابه
Effect of an ectonucleotidase inhibitor on anticonvulsant actions of low-frequency electrical stimulation in perforant path rapid kindling in rats
Introduction: Considering high prevalence of epileptic disease and considering that 40 percent of epileptic patients are resistant to drug therapy, it needs more researches to find new therapeutic ways. LFS is among the new methods for epilepsy treatments. One possible mechanism involved in the anticonvulsant effect of LFS is increased adenosine. Therefore, in this study the role of adenosin...
متن کاملTherapeutic effect of low frequency electric stimulation on the epileptogenic focus in amygdale-kindled rats.
This study was to examine the therapeutic effect of low-frequency electric stimulation (LFS) on the epileptogenic focus in amygdale-kindled rats, and to find out the optimal stimulus parameters. A microelectrode was implanted into the right amygdale of adult male rats. After fully kindling, LFS was delivered to the right amygdale (through the electrode) between seizures to induce stimulus train...
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nitric oxide (no) is a small molecule synthesized by most of mammalian cells with diverse biological activities including vasodilatation, host defense and wound healing. impaired wound healing is a common occurrence among diabetics and patients receiving glucocorticoid therapy. on the other hand the application of laser in biomedical area have been increased. thus, the current studies were desi...
15 صفحه اولLow-frequency Stimulation Decreases Hyperexcitability through Adenosine A1 Receptors in the Hippocampus of Kindled Rats
Introduction: In this study, the role of A1 adenosine receptors in improving the effect of Low-Frequency Electrical Stimulation (LFS) on seizure-induced hyperexcitability of hippocampal CA1 pyramidal neurons was investigated. Methods: A semi-rapid hippocampal kindling model was used to induce seizures in male Wistar rats. Examination of the electrophysiological properties of CA1 pyramidal neur...
متن کاملAnti-inflammatory and anti-oxidative effects of Myrtenol in the rats with allergic asthma
Abstract Aims: To investigate the effect of Myrtenol, the active ingredient of Myrtle, on the oxidant and anti-oxidant indices and cytokines in the allergic asthma. Methods: Allergic asthma was induced by ovalbumin (OVA) sensitization and inhalation in four groups of rats; Control, Asthma, Asthma+Dexamethasone and Asthma+Myrtenol. Myrtenol (50mg/kg) or Dexamethasone (2.5mg/kg) was a...
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ژورنال
عنوان ژورنال: Acta Pharmacologica Sinica
سال: 2015
ISSN: 1671-4083,1745-7254
DOI: 10.1038/aps.2015.45